Tuberous Sclerosis Complex (Renal)

Multisystem genetic disorder with angiomyolipomas and cysts in kidneys.

What it is

A genetic condition causing benign tumors and cysts across organs, with kidneys commonly affected.

Prevalence

Kidney involvement occurs in 70–80% of children with TSC, most often during childhood or adolescence.

Symptoms to watch

Angiomyolipomas, renal cysts, occasional bleeding, anemia, rare renal cell carcinoma, high blood pressure.

Treatment options

Embolization for bleeding AMLs, surgery when necessary, everolimus to slow tumor growth, blood-pressure control, dialysis, and transplant in severe cases.

Tuberous Sclerosis Complex (Renal)

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