Hemolytic Uremic Syndrome
Microangiopathy linking infection, anemia, and acute kidney injury.
What it is
A condition marked by hemolytic anemia, thrombocytopenia, and acute kidney injury, often following GI illness.
Prevalence
0.6–0.8 cases per 100,000 children annually, rising to 1.9–2.9 per 100,000 in children under five.
Symptoms to watch
Bloody diarrhea, fever, vomiting, lethargy, irritability, decreased urine output, pale skin, neurologic changes.
Treatment options
Fluids and electrolytes, transfusions, dialysis, medications (including eculizumab), intensive care, nutrition support, transplant if kidneys fail.
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